Bromide ion → 6-chloro-4-cyclopropyl-4-isobutyl-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one

HRID 811253Notes

Reaction equation

[Br-:33].[CH2:34]([CH:35]([CH3:36])[CH3:37])[Mg+:38].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[CH3:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1.[Cl:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[NH:8][C:7](=[O:12])[N:6]([CH2:13][C:14]([F:15])([F:16])[F:17])[C:5]2([OH:18])[CH:19]1[CH2:20][CH2:21]1.[S:29]([Cl:30])([Cl:31])=[O:32]>>[Cl:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[NH:8][C:7](=[O:12])[N:6]([CH2:13][C:14]([F:15])([F:16])[F:17])[C:5]2([CH:19]1[CH2:20][CH2:21]1)[CH2:34][CH:35]([CH3:36])[CH3:37]