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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 811475Generated: October 31, 2026

Dichloromethane → 7-Dimethylamino-8-(2-fluoro-phenyl)-4-(3-pyridin-4-yl-phenyl)-1,3-dihydro-benzo[b][1,4]diazepin-2-one

https://huagongshe.com/reaction/811475

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactant{2-Dimethylamino-2'-fluoro-5-(3-oxo-3-(3-pyridin-4-yl-phenyl)-propionylamino]-biphenyl-4-yl}-carbamic acid tert-butyl esterHCID 86589252—
Product7-Dimethylamino-8-(2-fluoro-phenyl)-4-(3-pyridin-4-yl-phenyl)-1,3-dihydro-benzo[b][1,4]diazepin-2-oneHCID 22317357—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-43918eebf31c4481a0fe16eb3cdc7310
Source noteTest data from https://doi.org/10.1039/C8SC04228D