Methanol → N,N-Dimethyl-4-(5,6,7,8-tetrahydropyrazolo[3,4-d]azepin-2(4H)-yl)benzamide

HRID 811493Notes

Reaction equation

HRID 811493 reaction equation
[CH3:1][N:2]([C:3](=[O:4])[c:5]1[cH:6][cH:7][c:8](-[n:11]2[n:12][c:13]3[c:19]([cH:20]2)[CH2:18][CH2:17][N:16]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:15][CH2:14]3)[cH:9][cH:10]1)[CH3:28].[CH3:39][OH:40].[Cl:36][CH2:37][Cl:38].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[CH3:1][N:2]([C:3](=[O:4])[c:5]1[cH:6][cH:7][c:8](-[n:11]2[n:12][c:13]3[c:19]([cH:20]2)[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]3)[cH:9][cH:10]1)[CH3:28]

Participants

5

Reactant 4

HCID 887MethanolHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 669309031,1-Dimethylethyl 2-{4-[(dimethylamino)carbonyl]phenyl}-4,5,7,8-tetrahydropyrazolo[3,4-d]azepine-6(2H)-carboxylate

Product 1

HCID 66930795N,N-Dimethyl-4-(5,6,7,8-tetrahydropyrazolo[3,4-d]azepin-2(4H)-yl)benzamide

Sources & evidence

ORD record
ord-30a88ce3e3f149b7847f5e9677561bc3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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