Potassium Cation → (5-Methyl-2-{[6-methoxy-7-(3-morpholinopropoxy)-4-quinolyl]oxy}phenyl)(phenyl)methanone

HRID 811662Notes

Reaction equation

HRID 811662 reaction equation
[C:40](=[O:41])([O-:42])[O-:43].[CH2:34]1[CH2:35][O:36][CH2:37][CH2:38][NH:39]1.[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[Cl:1][CH2:2][CH2:3][CH2:4][O:5][c:6]1[c:7]([O:32][CH3:33])[cH:8][c:9]2[c:10]([O:16][c:17]3[c:18]([C:24](=[O:25])[c:26]4[cH:27][cH:28][cH:29][cH:30][cH:31]4)[cH:19][c:20]([CH3:23])[cH:21][cH:22]3)[cH:11][cH:12][n:13][c:14]2[cH:15]1.[K+:44].[K+:45].[OH2:46]>>[CH2:2]([CH2:3][CH2:4][O:5][c:6]1[c:7]([O:32][CH3:33])[cH:8][c:9]2[c:10]([O:16][c:17]3[c:18]([C:24](=[O:25])[c:26]4[cH:27][cH:28][cH:29][cH:30][cH:31]4)[cH:19][c:20]([CH3:23])[cH:21][cH:22]3)[cH:11][cH:12][n:13][c:14]2[cH:15]1)[N:39]1[CH2:34][CH2:35][O:36][CH2:37][CH2:38]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 8083MorpholineHCID 19660Carbonate IonHCID 57756383(2-{[7-(3-Chloropropoxy)-6-methoxy-4-quinolyl]oxy}-5-methylphenyl)(phenyl)methanone

Product 1

HCID 23078569(5-Methyl-2-{[6-methoxy-7-(3-morpholinopropoxy)-4-quinolyl]oxy}phenyl)(phenyl)methanone

Sources & evidence

ORD record
ord-e30f351ecead479ea064ade56372ad3b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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