Trifluoroacetic acid → 4-Isopropoxy-3-[4-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-piperazine-1-carbonyl]-benzonitrile
Reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([O:12][CH:13]([CH3:14])[CH3:15])[c:7]([C:8](=[O:9])[OH:10])[cH:11]1.[F:16][C:17]([F:18])([F:19])[C:20]([OH:21])=[O:22].[F:23][C:24]([c:25]1[n:26][n:27][c:28]([N:30]2[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]2)[s:29]1)([F:36])[F:37]>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([O:12][CH:13]([CH3:14])[CH3:15])[c:7]([C:8](=[O:10])[N:33]2[CH2:32][CH2:31][N:30]([c:28]3[n:27][n:26][c:25]([C:24]([F:23])([F:36])[F:37])[s:29]3)[CH2:35][CH2:34]2)[cH:11]1Participants
4
Sources & evidence
- ORD record
- ord-7843487d9aee40d08e7865e4b6ef6186
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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