Methanol → N-{1,1-dimethyl-2-oxo-2-[4-(2-trifluoromethyl-benzoyl)-piperazin-1-yl]-ethyl}-4-hydroxy-benzamide
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([C:13](=[O:14])[NH:15][C:16]([C:17]([N:18]2[CH2:19][CH2:20][N:21]([C:24]([c:25]3[c:26]([C:31]([F:32])([F:33])[F:34])[cH:27][cH:28][cH:29][cH:30]3)=[O:35])[CH2:22][CH2:23]2)=[O:36])([CH3:37])[CH3:38])[cH:39][cH:40]1.[CH3:41][OH:42].[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48]>>[OH:8][c:9]1[cH:10][cH:11][c:12]([C:13](=[O:14])[NH:15][C:16]([C:17]([N:18]2[CH2:19][CH2:20][N:21]([C:24]([c:25]3[c:26]([C:31]([F:32])([F:33])[F:34])[cH:27][cH:28][cH:29][cH:30]3)=[O:35])[CH2:22][CH2:23]2)=[O:36])([CH3:37])[CH3:38])[cH:39][cH:40]1Participants
4
Sources & evidence
- ORD record
- ord-9454f6495f1949ac830eb169ff966239
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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