Ethanol → 3-Chloro-1-(4-isopropoxyphenyl)-5-(5-trifluoromethylpyridin-2-yl)indole-2-carboxylic acid ethyl ester

HRID 811931Notes

Reaction equation

[Br:29][c:30]1[n:31][cH:32][c:33]([C:36]([F:37])([F:38])[F:39])[cH:34][cH:35]1.[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[n:7](-[c:19]2[cH:20][cH:21][c:22]([O:25][CH:26]([CH3:27])[CH3:28])[cH:23][cH:24]2)[c:8]2[cH:9][cH:10][c:11]([B:16]([OH:17])[OH:18])[cH:12][c:13]2[c:14]1[Cl:15].[CH3:132][c:133]1[cH:134][cH:135][cH:136][cH:137][cH:138]1.[CH3:46][CH2:47][OH:48].[CH3:49][CH2:50][O:51][C:52]([CH3:53])=[O:54].[Na+:40].[Na+:41].[O-:42][C:43](=[O:44])[O-:45].[cH:55]1[cH:56][cH:57][c:58]([P:59]([Pd:60]([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)([P:80]([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[P:99]([c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)([c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)[c:112]2[cH:113][cH:114][cH:115][cH:116][cH:117]2)([c:118]2[cH:119][cH:120][cH:121][cH:122][cH:123]2)[c:124]2[cH:125][cH:126][cH:127][cH:128][cH:129]2)[cH:130][cH:131]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[n:7](-[c:19]2[cH:20][cH:21][c:22]([O:25][CH:26]([CH3:27])[CH3:28])[cH:23][cH:24]2)[c:8]2[cH:9][cH:10][c:11](-[c:30]3[n:31][cH:32][c:33]([C:36]([F:37])([F:38])[F:39])[cH:34][cH:35]3)[cH:12][c:13]2[c:14]1[Cl:15]