Hydrochloric Acid → N-[2-(5-Chloro-2-phenylbenzo[b]thiophen-3-yl)ethyl]acetamide

HRID 812088Notes

Reaction equation

HRID 812088 reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[CH3:27][C:28]([Cl:29])=[O:30].[Cl:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([c:8]([CH2:17][CH2:18][NH2:19])[c:9](-[c:11]3[cH:12][cH:13][cH:14][cH:15][cH:16]3)[s:10]2)[cH:20]1.[Cl:31][CH2:32][Cl:33].[ClH:1].[K+:25].[K+:26].[OH2:34]>>[Cl:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([c:8]([CH2:17][CH2:18][NH:19][C:28]([CH3:27])=[O:30])[c:9](-[c:11]3[cH:12][cH:13][cH:14][cH:15][cH:16]3)[s:10]2)[cH:20]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 962WaterHCID 6344DichloromethaneHCID 6367Acetyl chlorideHCID 19660Carbonate IonHCID 124121832-(5-Chloro-2-phenyl-1-benzothiophen-3-yl)ethanamine

Product 1

HCID 21917005N-[2-(5-Chloro-2-phenylbenzo[b]thiophen-3-yl)ethyl]acetamide

Sources & evidence

ORD record
ord-6024608c59654988814bef7d0d166255
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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