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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 812101Generated: October 31, 2026

Water → ethyl 5-[2-fluoro-4-(2-methoxy-4,6-dimethylpyridin-3-yl)phenyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylate

https://huagongshe.com/reaction/812101

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantCarbonate IonHCID 19660—
Reactant1,4-DioxaneHCID 31275—
ReactantCesium cationHCID 104967—
Reactant3-Bromo-2-methoxy-4,6-dimethylpyridineHCID 86686331—
Reactant5-Bromo-4,6-dimethylpicolinonitrileHCID 86686346—
Reactantethyl 5-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylateHCID 86686364—
ReactantHCID 178420554HCID 178420554—
Productethyl 5-[2-fluoro-4-(2-methoxy-4,6-dimethylpyridin-3-yl)phenyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxylateHCID 86686363—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-2ebf8191e0a14814834e7349638fd0c2
Source noteTest data from https://doi.org/10.1039/C8SC04228D