Hydrochloric Acid → 4-{6-Methoxy-7-[3-(4-methyl-piperazin-1-yl)-propoxy]-quinazolin-4-yl}-piperidine-1-carboxylic acid (4-pyrrolidin-1-yl-phenyl)-amide
Reaction equation
[C:1]([CH3:3])([CH3:4])([O:5][C:6](=[O:2])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:26][CH2:27][CH2:28][CH2:29][N:30]4[CH2:31][CH2:32][N:33]([CH3:36])[CH2:34][CH2:35]4)[c:21]([O:24][CH3:25])[cH:22][c:23]23)[CH2:12][CH2:13]1)[CH3:7].[ClH:37].[N+:38]([c:39]1[cH:40][cH:41][c:42]([O:43][C:44](=[O:45])[NH:49][c:50]2[cH:51][cH:52][c:53]([N:56]3[CH2:57][CH2:58][CH2:59][CH2:60]3)[cH:54][cH:55]2)[cH:46][cH:47]1)([O-:48])=[O:61]>>[O:5]=[C:6]([N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:26][CH2:27][CH2:28][CH2:29][N:30]4[CH2:31][CH2:32][N:33]([CH3:36])[CH2:34][CH2:35]4)[c:21]([O:24][CH3:25])[cH:22][c:23]23)[CH2:12][CH2:13]1)[NH:49][c:50]1[cH:51][cH:52][c:53]([N:56]2[CH2:57][CH2:58][CH2:59][CH2:60]2)[cH:54][cH:55]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-2adf60d1e8634de8a07151253e440df5
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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