Hydrochloric Acid → 2-[2-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-4,5,7,8-tetrahydro-1H-imidazo[4,5-d]azepin-6-yl]-acetamide

HRID 812226Notes

Reaction equation

HRID 812226 reaction equation
[Br:29][CH2:30][C:31](=[O:32])[NH2:33].[CH3:2][O:3][c:4]1[cH:5][cH:6][c:7]([N:23]2[CH2:24][CH2:25][O:26][CH2:27][CH2:28]2)[c:8]2[c:9]1[n:10][c:11](-[c:13]1[n:14][c:15]3[c:16]([nH:22]1)[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]3)[s:12]2.[CH3:42][C:43]#[N:44].[ClH:1].[I-:41].[Na+:34].[Na+:35].[Na+:40].[O-:36][C:37](=[O:38])[O-:39]>>[CH3:2][O:3][c:4]1[cH:5][cH:6][c:7]([N:23]2[CH2:24][CH2:25][O:26][CH2:27][CH2:28]2)[c:8]2[c:9]1[n:10][c:11](-[c:13]1[n:14][c:15]3[c:16]([nH:22]1)[CH2:17][CH2:18][N:19]([CH2:30][C:31](=[O:32])[NH2:33])[CH2:20][CH2:21]3)[s:12]2

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 923Sodium ion3×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 30165Iodide IonHCID 696322-BromoacetamideHCID 114415914-[2-(1,4,5,6,7,8-Hexahydroimidazo[4,5-d]azepin-2-yl)-4-methoxy-1,3-benzothiazol-7-yl]morpholine

Product 1

HCID 219192372-[2-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-4,5,7,8-tetrahydro-1H-imidazo[4,5-d]azepin-6-yl]-acetamide

Sources & evidence

ORD record
ord-1a3ced1336654d8187624c0d1c5728c9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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