3-(3-chloropropyl)-5-methyl-2,4(1H,3H)-pyrimidinedione → Hydrochloric Acid

HRID 812420Notes

Reaction equation

HRID 812420 reaction equation
[Cl:20][CH2:21][CH2:22][CH2:23][n:24]1[c:25](=[O:32])[nH:26][cH:27][c:28]([CH3:31])[c:29]1=[O:30].[OH:1][c:2]1[cH:3][c:4]([O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[c:5]([N:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:6][cH:7]1>>[ClH:20].[OH:1][c:2]1[cH:3][c:4]([O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[c:5]([N:8]2[CH2:9][CH2:10][N:11]([CH2:21][CH2:22][CH2:23][n:24]3[c:25](=[O:32])[nH:26][cH:27][c:28]([CH3:31])[c:29]3=[O:30])[CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

4

Reactant 2

HCID 110418353-(3-chloropropyl)-5-methyl-2,4(1H,3H)-pyrimidinedioneHCID 702010041-[4-Hydroxy-2-(2,2,2-trifluoroethoxy)phenyl]piperazine

Product 2

HCID 313Hydrochloric AcidHCID 701982373-[3-[4-[4-hydroxy-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-5-methyl-1H-pyrimidine-2,4-dione

Sources & evidence

ORD record
ord-e3ca45d8acd94cb4bff601ad952c0c87
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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