Acetone → 2-(1-(4-Bromophenyl)-3-oxocyclobutyl)isoindoline-1,3-dione

HRID 812421Notes

Reaction equation

HRID 812421 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([N:16]3[C:17](=[O:26])[c:18]4[cH:19][cH:20][cH:21][cH:22][c:23]4[C:24]3=[O:25])[CH2:9][C:10]3([CH2:11]2)[O:12][CH2:15][CH2:14][O:13]3)[cH:6][cH:7]1.[CH3:39][C:40](=[O:41])[CH3:42].[CH3:43][CH2:44][O:45][C:46]([CH3:47])=[O:48].[OH2:27].[c:28]1([CH3:29])[c:30]([S:31]([OH:32])(=[O:33])=[O:34])[cH:35][cH:36][cH:37][cH:38]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([N:16]3[C:17](=[O:26])[c:18]4[cH:19][cH:20][cH:21][cH:22][c:23]4[C:24]3=[O:25])[CH2:9][C:10](=[O:12])[CH2:11]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 962WaterHCID 69252-Methylbenzenesulfonic acidHCID 8857Ethyl AcetateHCID 582166062-(2-(4-Bromophenyl)-5,8-dioxaspiro[3.4]octan-2-yl)isoindoline-1,3-dione

Product 1

HCID 582165742-(1-(4-Bromophenyl)-3-oxocyclobutyl)isoindoline-1,3-dione

Sources & evidence

ORD record
ord-143ecf3678e54024a9636413445e276c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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