Water → (+)-Ethyl 2-ethoxy-3-[4-[2-[4-oxo-3,4-dihydro-1,3-benzoxazin-3-yl]ethoxy]phenyl]propanoate

HRID 812612Notes

Reaction equation

HRID 812612 reaction equation
[CH2:34]([CH3:35])[O:36][CH:37]([C:38](=[O:39])[O:40][CH2:41][CH3:42])[CH2:43][c:44]1[cH:45][cH:46][c:47]([OH:50])[cH:48][cH:49]1.[CH3:52][c:53]1[cH:54][cH:55][cH:56][cH:57][cH:58]1.[OH2:51].[OH:1][CH2:2][CH2:3][N:4]1[CH2:5][O:6][c:7]2[c:8]([cH:11][cH:12][cH:13][cH:14]2)[C:9]1=[O:10].[c:15]1([P:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[O:1]([CH2:2][CH2:3][N:4]1[CH2:5][O:6][c:7]2[c:8]([cH:11][cH:12][cH:13][cH:14]2)[C:9]1=[O:10])[c:47]1[cH:46][cH:45][c:44]([CH2:43][CH:37]([O:36][CH2:34][CH3:35])[C:38](=[O:39])[O:40][CH2:41][CH3:42])[cH:49][cH:48]1

Participants

6

Reactant 5

HCID 962WaterHCID 1140TolueneHCID 11776TriphenylphosphineHCID 37597024H-1,3-Benzoxazin-4-one, 2,3-dihydro-3-(2-hydroxyethyl)-HCID 11791243Ethyl 2-ethoxy-3-(4-hydroxyphenyl)propanoate

Product 1

HCID 11090948(+)-Ethyl 2-ethoxy-3-[4-[2-[4-oxo-3,4-dihydro-1,3-benzoxazin-3-yl]ethoxy]phenyl]propanoate

Sources & evidence

ORD record
ord-8002e70d10444f649427fa6e234f105d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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