Sodium ion → 9H-fluoren-9-ylmethyl-6-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]-2,4,4-trimethyl-2H-3,1-benzoxazine-1(4H)-carboxylate

HRID 812774Notes

Reaction equation

HRID 812774 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[cH:9][cH:10][cH:11][c:12]1-[c:13]1[cH:14][cH:15][c:16]2[c:17]([cH:25]1)[C:18]([CH3:23])([CH3:24])[O:19][CH:20]([CH3:22])[NH:21]2.[CH3:50][CH2:51][O:52][C:53](=[O:54])[CH3:55].[Cl:26][C:27](=[O:28])[O:29][CH2:30][CH:31]1[c:32]2[cH:33][cH:34][cH:35][cH:36][c:37]2-[c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]21.[Na+:44].[Na+:45].[O-:46][C:47](=[O:48])[O-:49].[O:56]1[CH2:57][CH2:58][O:59][CH2:60][CH2:61]1.[OH2:62]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[n:8]1[cH:9][cH:10][cH:11][c:12]1-[c:13]1[cH:14][cH:15][c:16]2[c:17]([cH:25]1)[C:18]([CH3:23])([CH3:24])[O:19][CH:20]([CH3:22])[N:21]2[C:27](=[O:28])[O:29][CH2:30][CH:31]1[c:32]2[cH:33][cH:34][cH:35][cH:36][c:37]2-[c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]21

Participants

8

Reactant 7

HCID 923Sodium ion2×HCID 962WaterHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 343679-Fluorenylmethyl chloroformateHCID 54467598tert-Butyl-5-(2,4,4-trimethyl-1,4-dihydro-2H-3,1-benzoxazin-6-yl)-1H-pyrrole-1-carboxylate

Product 1

HCID 183745569H-fluoren-9-ylmethyl-6-[1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl]-2,4,4-trimethyl-2H-3,1-benzoxazine-1(4H)-carboxylate

Sources & evidence

ORD record
ord-cee0b1722e6c4d9dbd9400e76f3eabb6
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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