Acetyl chloride → 1-(2-(1,2,3,4-Tetrahydro-1-acetylquinolin-4-yl)ethyl)-4-(3,4-dimethoxyphenyl)piperidine
Reaction equation
[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:29][C:30]([Cl:31])=[O:32].[NH:1]1[CH2:2][CH2:3][CH:4]([CH2:11][CH2:12][N:13]2[CH2:14][CH2:15][CH:16]([c:19]3[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[cH:23][cH:24]3)[CH2:17][CH2:18]2)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21>>[N:1]1([C:30]([CH3:29])=[O:32])[CH2:2][CH2:3][CH:4]([CH2:11][CH2:12][N:13]2[CH2:14][CH2:15][CH:16]([c:19]3[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[cH:23][cH:24]3)[CH2:17][CH2:18]2)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21Participants
4
Sources & evidence
- ORD record
- ord-8cb078f9ac3f4df0ae60651e38b6e98e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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