Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 812985Generated: October 29, 2026

p-Bromochlorobenzene → Tert-butyl 8-(4-chlorophenyl)-8-hydroxy-5-azaspiro[2.5]octane-5-carboxylate

https://huagongshe.com/reaction/812985

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-BromochlorobenzeneHCID 7806—
ReactantTetrahydrofuranHCID 8028—
Reactanttert-Butyl 8-oxo-5-azaspiro(2.5)octane-5-carboxylateHCID 57889898—
ReactantButyllithiumHCID 178418339—
ProductTert-butyl 8-(4-chlorophenyl)-8-hydroxy-5-azaspiro[2.5]octane-5-carboxylateHCID 57889946—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-6df23e8ad31a4cc1bbefc200b53d10f7
Source noteTest data from https://doi.org/10.1039/C8SC04228D