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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 813115Generated: October 26, 2026

Hydrochloric Acid → 6-(1-Acetylpiperidin-4-yloxy)-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazoline

https://huagongshe.com/reaction/813115

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantAcetyl chlorideHCID 6367—
ReactantDiisopropylethylamineHCID 81531—
ReactantN-(3-chloro-2-fluorophenyl)-7-methoxy-6-(piperidin-4-yloxy)quinazolin-4-amineHCID 10408840—
Product6-(1-Acetylpiperidin-4-yloxy)-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolineHCID 10433617—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-9e00eee30d9d4530891d940353197406
Source noteTest data from https://doi.org/10.1039/C8SC04228D