Hydrochloric Acid → 1-(4-Bromophenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline

HRID 813138Notes

Reaction equation

HRID 813138 reaction equation
[BH4-:1].[Br:3][c:4]1[cH:5][cH:6][c:7]([C:10]2=[N:11][CH2:12][CH2:13][c:14]3[cH:15][c:16]([O:20][CH3:21])[cH:17][cH:18][c:19]32)[cH:8][cH:9]1.[CH3:23][OH:24].[ClH:22].[Na+:2]>>[Br:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[NH:11][CH2:12][CH2:13][c:14]3[cH:15][c:16]([O:20][CH3:21])[cH:17][cH:18][c:19]32)[cH:8][cH:9]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 887MethanolHCID 923Sodium ionHCID 28123BorohydrideHCID 118232271-(4-Bromo-phenyl)-6-methoxy-3,4-dihydro-isoquinoline

Product 1

HCID 43161381-(4-Bromophenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-605ddbc372af49e9b29a0525eba9dd2a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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