Acetate → tert-Butyl 4-(2-(4-aminophenoxy)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-1-carboxylate
Reaction equation
[C:54]([O-:55])(=[O:56])[CH3:57].[C:59]([O-:60])(=[O:61])[CH3:62].[CH2:47]1[O:48][CH2:49][CH2:50][O:51][CH2:52]1.[CH3:18][C:19]1([CH3:20])[C:21]([CH3:22])([CH3:23])[O:24][B:25]([c:26]2[c:27]([O:32][c:33]3[cH:34][cH:35][c:36]([NH2:39])[cH:37][cH:38]3)[n:28][cH:29][cH:30][cH:31]2)[O:40]1.[CH3:63][CH2:64][O:65][C:66]([CH3:67])=[O:68].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[n:8]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[cH:9][cH:10]2.[Na+:41].[Na+:42].[O-:43][C:44](=[O:45])[O-:46].[OH2:53].[Pd+2:58]>>[c:2]1(-[c:26]2[c:27]([O:32][c:33]3[cH:34][cH:35][c:36]([NH2:39])[cH:37][cH:38]3)[n:28][cH:29][cH:30][cH:31]2)[c:3]2[c:4]([n:5][cH:6][cH:7]1)[n:8]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[cH:9][cH:10]2Participants
10
Reactant 9
HCID 175Acetate2×
HCID 923Sodium ion2×
HCID 962Water
HCID 8857Ethyl Acetate
HCID 19660Carbonate Ion
HCID 312751,4-Dioxane
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)
HCID 247767911-Boc-4-chloro-7-azaindole
HCID 574164444-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yloxy)benzenamineProduct 1
Sources & evidence
- ORD record
- ord-82857ee6fee3433f8c2b3f687a7ee1b5
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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