HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58522649, compound → 7-Amino-2,3-dimethyl-2,3-dihydro-isoindol-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58522649 | HCID 58522649 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 7-Amino-2,3-dimethyl-2,3-dihydro-isoindol-1-one | HCID 58522621 | — |
Reaction Steps
2-methyl-3-methylene-7-nitro-2,3-dihydro-isoindol-1-one (13.96 g) is suspended in THF and mixed with a spatula tip of Pd/C (5%) and hydrogenated under H2 pressure (3 bar). For working up the catalyst is filtered off and the solvent is eliminated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846689B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-0d9aab6fc3f4402fbdd6efe9a31e7721 |
| Source note | uspto-grants-2014_09 |