Ethyl Acetate → N-(3,5-Bis-trifluoromethyl-phenyl)-4-(2,5-dichloro-phenoxy)-nicotinamide

HRID 813444Notes

Reaction equation

HRID 813444 reaction equation
[C:43]([O:44][CH2:45][CH3:46])(=[O:47])[CH3:48].[CH3:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH3:55].[Cl:1][c:2]1[c:3]([O:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[c:14]4[c:15]([cH:16][cH:17][cH:18][cH:19]4)[CH2:20][CH2:21][CH2:22]3)[cH:7][n:8][cH:9][cH:10]2)[cH:23][c:24]([Cl:27])[cH:25][cH:26]1.[F:28][C:29]([c:30]1[cH:31][c:32]([NH2:33])[cH:34][c:35]([C:37]([F:38])([F:39])[F:40])[cH:36]1)([F:41])[F:42]>>[Cl:1][c:2]1[c:3]([O:4][c:5]2[c:6]([C:11](=[O:12])[NH:33][c:32]3[cH:31][c:30]([C:29]([F:28])([F:41])[F:42])[cH:36][c:35]([C:37]([F:38])([F:39])[F:40])[cH:34]3)[cH:7][n:8][cH:9][cH:10]2)[cH:23][c:24]([Cl:27])[cH:25][cH:26]1

Participants

5

Reactant 4

HCID 8857Ethyl AcetateHCID 8900HeptaneHCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 53311781[4-(2,5-Dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone

Product 1

HCID 86655953N-(3,5-Bis-trifluoromethyl-phenyl)-4-(2,5-dichloro-phenoxy)-nicotinamide

Sources & evidence

ORD record
ord-89dbb44663234cf0bea0c816bc6f39b9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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