Dichloromethane → 8-(4-Fluoro-phenyl)-4-(3-nitro-phenyl)-1,3-dihydro-benzo[b][1,4]diazepin-2-one

HRID 813484Notes

Reaction equation

HRID 813484 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:21][C:22]([CH2:23][C:24](=[O:5])[c:26]2[cH:27][c:28]([N+:32](=[O:33])[O-:34])[cH:29][cH:30][cH:31]2)=[O:35])[cH:10][c:11](-[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[cH:12][cH:13]1)([CH3:6])([CH3:25])[CH3:36].[Cl:44][CH2:45][Cl:46].[F:37][C:38]([F:39])([F:40])[C:41]([OH:42])=[O:43]>>[N:7]1=[C:24]([c:26]2[cH:27][c:28]([N+:32](=[O:33])[O-:34])[cH:29][cH:30][cH:31]2)[CH2:23][C:22](=[O:35])[NH:21][c:9]2[c:8]1[cH:13][cH:12][c:11](-[c:14]1[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]1)[cH:10]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 86588028HCID 86588028, compound

Product 1

HCID 222248198-(4-Fluoro-phenyl)-4-(3-nitro-phenyl)-1,3-dihydro-benzo[b][1,4]diazepin-2-one

Sources & evidence

ORD record
ord-77145f07f6074bb28685404bfe11af70
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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