Hydrochloric Acid → 2-(4-(Piperazin-1-yl)phenyl)pyrimidine

HRID 813755Notes

Reaction equation

HRID 813755 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17](-[c:20]3[n:21][cH:22][cH:23][cH:24][n:25]3)[cH:18][cH:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:33][CH2:34][Cl:35].[ClH:26].[O:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17](-[c:20]3[n:21][cH:22][cH:23][cH:24][n:25]3)[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 59511347tert-Butyl 4-(4-(pyrimidin-2-yl)phenyl)piperazine-1-carboxylate

Product 1

HCID 534203192-(4-(Piperazin-1-yl)phenyl)pyrimidine

Sources & evidence

ORD record
ord-7a087c1190354bdc95a058aef1969c5f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…