Tetrahydrofuran → 8-Ethynyl-1,4-dioxaspiro[4.5]decane
Reaction equation
[CH2:15]([Li:16])[CH2:17][CH2:18][CH3:19].[CH2:1]1[O:2][C:3]2([CH2:4][CH2:5][CH:6]([CH:9]=[C:10]([Br:11])[Br:12])[CH2:7][CH2:8]2)[O:13][CH2:14]1.[CH3:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30].[O:20]1[CH2:21][CH2:22][CH2:23][CH2:24]1>>[CH2:1]1[O:2][C:3]2([CH2:4][CH2:5][CH:6]([C:9]#[CH:10])[CH2:7][CH2:8]2)[O:13][CH2:14]1Participants
5
Sources & evidence
- ORD record
- ord-1ed187936c3b4c299d88862eaa917d05
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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