Chloroform → 2-(3-Chloro-2,5,6-trifluoropyridin-4-yl)-1H-isoindole-1,3(2H)-dione

HRID 813827Notes

Reaction equation

HRID 813827 reaction equation
[C:15]1(=[O:25])[c:16]2[c:17]([cH:21][cH:22][cH:23][cH:24]2)[C:18](=[O:20])[NH:19]1.[CH:27]([Cl:28])([Cl:29])[Cl:30].[Cl:1][CH2:2][Cl:3].[Cl:4][c:5]1[c:6]([F:14])[n:7][c:8]([F:13])[c:9]([F:12])[c:10]1[F:11].[K:26]>>[Cl:4][c:5]1[c:6]([F:14])[n:7][c:8]([F:13])[c:9]([F:12])[c:10]1[N:19]1[C:15](=[O:25])[c:16]2[c:17]([cH:21][cH:22][cH:23][cH:24]2)[C:18]1=[O:20]

Participants

6

Reactant 5

HCID 6212ChloroformHCID 6344DichloromethaneHCID 6809PhthalimideHCID 1371833-Chloro-2,4,5,6-tetrafluoropyridineHCID 5462222Potassium

Product 1

HCID 221212012-(3-Chloro-2,5,6-trifluoropyridin-4-yl)-1H-isoindole-1,3(2H)-dione

Sources & evidence

ORD record
ord-39a25a03b48843a0a65578e29b1bd17d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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