HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → [2,6-Dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | [2,6-Dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester | HCID 86679894 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | [2,6-Dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid | HCID 53262539 | — |
Reaction Steps
A solution of 77 mg of [2,6-dimethyl-4-(5-phenoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]-acetic acid tert-butyl ester in 0.7 ml of trifluoroacetic acid was stirred at room temperature for 2 h. Then 5 ml of toluene were added and the solvents were distilled off in vacuo. The residue was triturated with 2 ml of acetonitrile, and the title compound was isolated by filtration. Yield: 26 mg of a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846692B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-5e578cdd9770476982ded1f6e703006c |
| Source note | uspto-grants-2014_09 |