Hydrochloric Acid → 5-amino-N-tert-butyl-2-methylsulfanyl-4-[3-[(2-morpholin-4-ylacetyl)amino]phenyl]quinazoline-6-carboxamide
Reaction equation
[CH2:32]1[CH2:33][O:34][CH2:35][CH2:36][NH:37]1.[CH3:40][C:41]#[N:42].[Cl:43][CH2:44][Cl:45].[ClH:39].[NH2:1][c:2]1[c:3]2[c:4](-[c:21]3[cH:22][c:23]([NH:27][C:28]([CH2:29][Br:30])=[O:31])[cH:24][cH:25][cH:26]3)[n:5][c:6]([S:19][CH3:20])[n:7][c:8]2[cH:9][cH:10][c:11]1[C:12](=[O:13])[NH:14][C:15]([CH3:16])([CH3:17])[CH3:18].[OH2:38]>>[NH2:1][c:2]1[c:3]2[c:4](-[c:21]3[cH:22][c:23]([NH:27][C:28]([CH2:29][N:37]4[CH2:32][CH2:33][O:34][CH2:35][CH2:36]4)=[O:31])[cH:24][cH:25][cH:26]3)[n:5][c:6]([S:19][CH3:20])[n:7][c:8]2[cH:9][cH:10][c:11]1[C:12](=[O:13])[NH:14][C:15]([CH3:16])([CH3:17])[CH3:18]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fb410bd875ff4d9f80d2b87cff0cc27c
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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