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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 813938Generated: October 26, 2026

1,2-Dichloroethane → tert-butyl N-[6-(2,3-difluorophenyl)-1-(2-hydroxy-2-methylpropyl)-2-oxoazepan-3-yl]-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamate

https://huagongshe.com/reaction/813938

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantEthanolHCID 702—
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
Reactant1-Chloro-2-methylpropan-2-olHCID 68409—
ReactantDiisopropylethylamineHCID 81531—
Reactant6-Amino-2-[bis[(2-methylpropan-2-yl)oxycarbonyl]amino]-5-(2,3-difluorophenyl)hexanoic acidHCID 22293248—
Producttert-butyl N-[6-(2,3-difluorophenyl)-1-(2-hydroxy-2-methylpropyl)-2-oxoazepan-3-yl]-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamateHCID 178459286—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-4f8075fcb3bb414f8154bb5fa6ce7c73
Source noteTest data from https://doi.org/10.1039/C8SC04228D