Tetrahydrofuran → 1-(5-Methyl-thien-2-yl)3,4-dihydro-4,4-dimethyl-7-bromo-naphthalene

HRID 813962Notes

Reaction equation

HRID 813962 reaction equation
[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:12][C:13]1([CH3:25])[CH2:14][CH2:15][C:16](=[O:24])[c:17]2[cH:18][c:19]([Br:23])[cH:20][cH:21][c:22]21.[CH3:1][c:2]1[s:3][cH:4][cH:5][cH:6]1.[CH3:7][CH2:8][CH2:9][CH2:10][Li:11]>>[CH3:1][c:2]1[s:3][c:4]([C:16]2=[CH:15][CH2:14][C:13]([CH3:12])([CH3:25])[c:22]3[c:17]2[cH:18][c:19]([Br:23])[cH:20][cH:21]3)[cH:5][cH:6]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 111262-MethylthiopheneHCID 107533577-Bromo-4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-oneHCID 178418339Butyllithium

Product 1

HCID 186200621-(5-Methyl-thien-2-yl)3,4-dihydro-4,4-dimethyl-7-bromo-naphthalene

Sources & evidence

ORD record
ord-ffbe592fd6bb49838be5aac6dff21b45
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…