Pyrrolidine → 6-[5-(4-Chlorophenyl)pyridin-2-ylethynyl]-4-methyl-2-pyrrolidin-1-ylquinoline
Reaction equation
[CH2:1]1[CH2:2][CH2:3][NH:4][CH2:5]1.[CH2:33]1[O:34][CH2:35][CH2:36][O:37][CH2:38]1.[Cl:6][c:7]1[n:8][c:9]2[cH:10][cH:11][c:12]([C:18]#[C:19][c:20]3[n:21][cH:22][c:23](-[c:26]4[cH:27][cH:28][c:29]([Cl:32])[cH:30][cH:31]4)[cH:24][cH:25]3)[cH:13][c:14]2[c:15]([CH3:17])[cH:16]1>>[CH2:1]1[CH2:2][CH2:3][N:4]([c:7]2[n:8][c:9]3[cH:10][cH:11][c:12]([C:18]#[C:19][c:20]4[n:21][cH:22][c:23](-[c:26]5[cH:27][cH:28][c:29]([Cl:32])[cH:30][cH:31]5)[cH:24][cH:25]4)[cH:13][c:14]3[c:15]([CH3:17])[cH:16]2)[CH2:5]1Participants
4
Sources & evidence
- ORD record
- ord-d5ec1176a6824e50aa98c70080a12d22
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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