Dichloromethane → 3-[1-(3,5-Difluorophenyl)-2,2-dimethylpropyl]azetidine

HRID 814029Notes

Reaction equation

HRID 814029 reaction equation
[Cl:32][CH2:33][Cl:34].[F:1][c:2]1[cH:3][c:4]([CH:9]([C:10]([CH3:11])([CH3:12])[CH3:13])[CH:14]2[CH2:15][N:16]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:17]2)[cH:5][c:6]([F:8])[cH:7]1.[F:25][C:26]([F:27])([F:28])[C:29]([OH:30])=[O:31]>>[F:1][c:2]1[cH:3][c:4]([CH:9]([C:10]([CH3:11])([CH3:12])[CH3:13])[CH:14]2[CH2:15][NH:16][CH2:17]2)[cH:5][c:6]([F:8])[cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67066008HCID 67066008, compound

Product 1

HCID 670659743-[1-(3,5-Difluorophenyl)-2,2-dimethylpropyl]azetidine

Sources & evidence

ORD record
ord-7e367278ac814590a347ba1b04881237
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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