Dimethylformamide → Tert-butyl 2-bromo-4,5-dihydropyrido[4,3-b]thieno[2,3-d]oxepin-8-yl(tert-butyl)carbamate
Reaction equation
[Br:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8].[C:9]([CH3:10])([CH3:11])([CH3:12])[N:13]([C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[c:21]1[cH:22][c:23]2[c:29]([cH:30][n:31]1)-[c:28]1[c:27]([cH:34][cH:33][s:32]1)[CH2:26][CH2:25][O:24]2.[CH3:35][N:36]([CH3:37])[CH:38]=[O:39]>>[Br:1][c:33]1[s:32][c:28]2[c:27]([cH:34]1)[CH2:26][CH2:25][O:24][c:23]1[cH:22][c:21]([N:13]([C:9]([CH3:10])([CH3:11])[CH3:12])[C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[n:31][cH:30][c:29]1-2Participants
4
Sources & evidence
- ORD record
- ord-e4862e3ebb6e47108a3125dc2ec3b361
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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