Pyrrolidine → 5-Pyrrolidin-1-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([Br:17])[cH:14][c:15]2[CH2:16]1.[CH2:18]1[CH2:19][CH2:20][NH:21][CH2:22]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([N:21]3[CH2:20][CH2:19][CH2:18][CH2:22]3)[cH:14][c:15]2[CH2:16]1Participants
3
Sources & evidence
- ORD record
- ord-8b0fff1aa8934f1a837c0270d74c3aa9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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