Dichloromethane → 6-Chloro-N-methoxy-N-methylnicotinamide

HRID 814224Notes

Reaction equation

HRID 814224 reaction equation
[CH3:11][NH:12][O:13][CH3:14].[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[Cl:8])[cH:9][cH:10]1.[Cl:22][CH2:23][Cl:24]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[N:12]([CH3:11])[O:13][CH3:14])[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 14232N,O-DimethylhydroxylamineHCID 27821656-Chloronicotinoyl Chloride

Product 1

HCID 114355976-Chloro-N-methoxy-N-methylnicotinamide

Sources & evidence

ORD record
ord-5cf64a37f2d145df9b26a81f5d72550c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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