Hydrochloric Acid → N-(2-(2-Aminothiazol-5-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine

HRID 814399Notes

Reaction equation

HRID 814399 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[s:9][c:10]([CH2:13][CH2:14][NH:15][c:16]2[c:17]3[c:18]([n:19][cH:20][n:21]2)[cH:22][cH:23][s:24]3)[cH:11][n:12]1)([CH3:5])([CH3:6])[CH3:25].[CH2:27]1[O:28][CH2:29][CH2:30][O:31][CH2:32]1.[ClH:26]>>[NH2:7][c:8]1[s:9][c:10]([CH2:13][CH2:14][NH:15][c:16]2[c:17]3[c:18]([n:19][cH:20][n:21]2)[cH:22][cH:23][s:24]3)[cH:11][n:12]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 86603168{5-[2-(Thieno[3,2-d]pyrimidin-4-ylamino)-ethyl]-thiazol-2-yl}-carbamic acid tert-butyl ester

Product 1

HCID 44230296N-(2-(2-Aminothiazol-5-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-685d0a5cee374f2cb3d2d76cba4f860d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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