Methanol → N-[4-(benzyloxy)-3-methoxyphenyl]-5H-pyrrolo[3,2-d]pyrimidin-4-amine

HRID 814445Notes

Reaction equation

HRID 814445 reaction equation
[CH2:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[O:18][c:19]1[c:20]([O:26][CH3:27])[cH:21][c:22]([NH2:23])[cH:24][cH:25]1.[CH3:28][N:29]1[CH2:30][CH2:31][CH2:32][C:33]1=[O:34].[CH3:35][OH:36].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][nH:10]2>>[c:2]1([NH:23][c:22]2[cH:21][c:20]([O:26][CH3:27])[c:19]([O:18][CH2:11][c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[cH:25][cH:24]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][nH:10]2

Participants

5

Reactant 4

HCID 887MethanolHCID 13387N-methyl-2-pyrrolidoneHCID 272264-(Benzyloxy)-3-methoxyanilineHCID 53706954-chloro-5H-pyrrolo[3,2-d]pyrimidine

Product 1

HCID 57597328N-[4-(benzyloxy)-3-methoxyphenyl]-5H-pyrrolo[3,2-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-02e061bf04424db1ab1f0579163b7ff6
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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