Dichloromethane → 4-(4-Chlorophenyl)-4-methoxypiperidine

HRID 814638Notes

Reaction equation

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][C:11]([O:14][CH3:15])([c:16]2[cH:17][cH:18][c:19]([Cl:22])[cH:20][cH:21]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH2:30]([Cl:31])[Cl:32].[OH:23][C:24]([C:25]([F:26])([F:27])[F:28])=[O:29]>>[NH:8]1[CH2:9][CH2:10][C:11]([O:14][CH3:15])([c:16]2[cH:17][cH:18][c:19]([Cl:22])[cH:20][cH:21]2)[CH2:12][CH2:13]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 219975781-Tert-butoxycarbonyl-4-(4-chlorophenyl)-4-methoxypiperidine

Product 1

HCID 224946584-(4-Chlorophenyl)-4-methoxypiperidine

Sources & evidence

ORD record: ord-5067dc73c9fa4f4a8f7b3c91a36426eb
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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