Hydrochloric Acid → 1-[(5-Chloro-pyridin-2-ylcarbamoyl)-methyl]-4-(4,4-difluoro-piperidine-1-carbonyl)-1H-benzoimidazole-2-carboxylic acid (1-isopropyl-piperidin-4-yl)-amide
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9](=[O:10])[CH2:11][n:12]2[c:13]([C:24]([NH:25][CH:26]3[CH2:27][CH2:28][N:29]([CH:32]([CH3:33])[CH3:34])[CH2:30][CH2:31]3)=[O:35])[n:14][c:15]3[c:16]2[cH:17][cH:18][cH:19][c:20]3[C:21](=[O:22])[OH:23])[n:6][cH:7]1.[ClH:36].[F:37][C:38]1([F:44])[CH2:39][CH2:40][NH:41][CH2:42][CH2:43]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9](=[O:10])[CH2:11][n:12]2[c:13]([C:24]([NH:25][CH:26]3[CH2:27][CH2:28][N:29]([CH:32]([CH3:33])[CH3:34])[CH2:30][CH2:31]3)=[O:35])[n:14][c:15]3[c:16]2[cH:17][cH:18][cH:19][c:20]3[C:21](=[O:22])[N:41]2[CH2:40][CH2:39][C:38]([F:37])([F:44])[CH2:43][CH2:42]2)[n:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-205e9271c3cd41ada6a1cc35c77c0949
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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