HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54399474, compound → 5(S)Isoxazol-3-ylaminomethyl-3-(4-(2-methylimidazol-1-yl)-3-fluorophenyl)oxazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54399474 | HCID 54399474 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5(S)Isoxazol-3-ylaminomethyl-3-(4-(2-methylimidazol-1-yl)-3-fluorophenyl)oxazolidin-2-one | HCID 20725709 | 89.9% |
Reaction Steps
Using essentially the technique of Example 8, but starting from 3-(4-(2-methylimidazol-1-yl)-3-fluorophenyl)-5(R)—(N-(t-butoxycarbonyl)isoxazol-3-ylaminomethyl)oxazolidin-2-one (510 mg, 1.12 mM), and isolating finally by extraction into dichloromethane gave title product (358 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087629B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-20a119f7c3384c64958acee5a71e6e1a |
| Source note | uspto-grants-2006_08 |