Hydrochloric Acid → (RS)-1,4-Dibenzyl-piperidin-3-one

HRID 815074Notes

Reaction equation

HRID 815074 reaction equation
[CH2:1]([O:2][C:3](=[O:4])[C:6]1([CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[C:7](=[O:19])[CH2:8][N:9]([CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:10][CH2:11]1)[CH3:5].[CH3:30][CH2:31][OH:32].[ClH:27].[Na+:29].[OH-:28]>>[CH:6]1([CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[C:7](=[O:19])[CH2:8][N:9]([CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:10][CH2:11]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 15511748(SR)-1,4-dibenzyl-3-oxo-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 9922920(RS)-1,4-Dibenzyl-piperidin-3-one

Sources & evidence

ORD record
ord-7563fca3794e4723bf831549792e5279
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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