Tetrahydrofuran → Tert-butyl 4-[6-(2-fluoropyridine-3-carbonyl)pyrazin-2-yl]-2-(2-methylpropyl)piperazine-1-carboxylate
Reaction equation
[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[F:25][c:26]1[n:27][cH:28][cH:29][cH:30][c:31]1[C:32](=[O:33])[N:34]([O:35][CH3:36])[CH3:37].[I:1][c:2]1[cH:3][n:4][cH:5][c:6]([N:8]2[CH2:9][CH:10]([CH2:21][CH:22]([CH3:23])[CH3:24])[N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[n:7]1>>[c:2]1([C:32]([c:31]2[c:26]([F:25])[n:27][cH:28][cH:29][cH:30]2)=[O:33])[cH:3][n:4][cH:5][c:6]([N:8]2[CH2:9][CH:10]([CH2:21][CH:22]([CH3:23])[CH3:24])[N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[n:7]1Participants
4
Sources & evidence
- ORD record
- ord-42ac533b9ac6470c9fbfc695ad14201f
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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