Tetrahydrofuran → 2-Chloro-5-(3-hydroxy-4-methoxy-benzoyl)-benzenesulfonamide

HRID 816294Notes

Reaction equation

HRID 816294 reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][c:7]1[cH:8][c:9]([C:10](=[O:11])[c:12]2[cH:13][cH:14][c:15]([Cl:22])[c:16]([S:18](=[O:19])(=[O:20])[NH2:21])[cH:17]2)[cH:23][cH:24][c:25]1[O:26][CH3:27])([CH3:5])([CH3:28])[CH3:29].[CH3:31][CH2:32][CH2:33][CH2:34][N+:35]([CH2:36][CH2:37][CH2:38][CH3:39])([CH2:40][CH2:41][CH2:42][CH3:43])[CH2:44][CH2:45][CH2:46][CH3:47].[F-:30].[O:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1>>[OH:6][c:7]1[cH:8][c:9]([C:10](=[O:11])[c:12]2[cH:13][cH:14][c:15]([Cl:22])[c:16]([S:18](=[O:19])(=[O:20])[NH2:21])[cH:17]2)[cH:23][cH:24][c:25]1[O:26][CH3:27]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 581075125-[3-(tert-Butyl-dimethyl-silanyloxy)-4-methoxy-benzoyl]-2-chloro-benzenesulfonamide

Product 1

HCID 581074722-Chloro-5-(3-hydroxy-4-methoxy-benzoyl)-benzenesulfonamide

Sources & evidence

ORD record
ord-99819e932a93445cb6cb133a0bf8d850
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…