Piperazine → 1-[5-(4-Fluoro-Phenyl)-4-(2,2,2-Trifluoro-Ethoxymethyl)-Oxazol-2-yl]-Piperazine

HRID 816504Notes

Reaction equation

HRID 816504 reaction equation
[CH2:24]1[CH2:25][NH:26][CH2:27][CH2:28][NH:29]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH2:17][O:18][CH2:19][C:20]([F:21])([F:22])[F:23])[n:10][c:11]([S:13]([CH3:14])(=[O:15])=[O:16])[o:12]2)[cH:6][cH:7]1.[O:30]1[CH2:31][CH2:32][O:33][CH2:34][CH2:35]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH2:17][O:18][CH2:19][C:20]([F:21])([F:22])[F:23])[n:10][c:11]([N:26]3[CH2:25][CH2:24][NH:29][CH2:28][CH2:27]3)[o:12]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 4837PiperazineHCID 312751,4-DioxaneHCID 187004355-(4-Fluoro-phenyl)-2-methanesulfonyl-4-(2,2,2-trifluoro-ethoxymethyl)-oxazole

Product 1

HCID 187004001-[5-(4-Fluoro-Phenyl)-4-(2,2,2-Trifluoro-Ethoxymethyl)-Oxazol-2-yl]-Piperazine

Sources & evidence

ORD record
ord-770751c080ba4c0ba9ce938763e30a71
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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