Phosphorus oxychloride → 3-Chloromethyl-8-(2-fluorobenzyloxy)-2-methylimidazo[1,2-a]pyridine

HRID 816521Notes

Reaction equation

HRID 816521 reaction equation
[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[c:7]3[n:8]([cH:9][cH:10][cH:11]2)[c:12]([CH2:16][OH:17])[c:13]([CH3:15])[n:14]3)[cH:18][cH:19][cH:20][cH:21]1.[P:22]([Cl:23])([Cl:24])([Cl:25])=[O:26]>>[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[c:7]3[n:8]([cH:9][cH:10][cH:11]2)[c:12]([CH2:16][Cl:24])[c:13]([CH3:15])[n:14]3)[cH:18][cH:19][cH:20][cH:21]1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 20458963HCID 20458963, compound

Product 1

HCID 204589533-Chloromethyl-8-(2-fluorobenzyloxy)-2-methylimidazo[1,2-a]pyridine

Sources & evidence

ORD record
ord-adab36ab53794b3ea17d12aff47b9f9f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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