Acetone → 4-Benzyloxy-3-chloroaniline

HRID 816605Notes

Reaction equation

HRID 816605 reaction equation
[Br-:30].[C:10](=[O:11])([O-:12])[O-:13].[CH2:31]([N+:32]([CH2:33][CH2:34][CH2:35][CH3:36])([CH2:37][CH2:38][CH2:39][CH3:40])[CH2:41][CH2:42][CH2:43][CH3:44])[CH2:45][CH2:46][CH3:47].[CH3:26][C:27](=[O:28])[CH3:29].[Cl:16][CH2:17][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1.[K+:14].[K+:15].[K+:25].[NH2:1][c:2]1[cH:3][c:4]([Cl:9])[c:5]([OH:8])[cH:6][cH:7]1.[OH-:24]>>[NH2:1][c:2]1[cH:3][c:4]([Cl:9])[c:5]([O:8][CH2:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:6][cH:7]1

Participants

9

Reactant 8

HCID 180AcetoneHCID 259Bromide ionHCID 813Potassium Cation3×HCID 961HydroxideHCID 7503Benzyl ChlorideHCID 16028TetrabutylammoniumHCID 19660Carbonate IonHCID 775784-Amino-2-chlorophenol

Product 1

HCID 12682854-Benzyloxy-3-chloroaniline

Sources & evidence

ORD record
ord-1f63d7e304ee4160b7d47ff620a88362
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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