Ethylamine tetrahydrofuran → 6-({5-[2-(ethylamino)ethoxy]pyridin-2-yl}oxy)-N-(3-methyl-1,2,4-thiadiazol-5-yl)quinazoline-4-amine

Participants

Reaction Steps

Using 6-{[5-(2,2-diethoxyethoxy)pyridin-2-yl]oxy}-N-(3-methyl-1,2,4-thiadiazol-5-yl)quinazoline-4-amine obtained in Example 47 and 2 M ethylamine/tetrahydrofuran solution, and in the same manner as in Example 47 or according to a method similar to it or according to a combination thereof with an ordinary method, the entitled compound (24 mg) was obtained as a yellow solid.

Provenance & Evidence