Trifluoroacetic acid → 4-(Piperidin-4-yl)butanamide

HRID 816823Notes

Reaction equation

HRID 816823 reaction equation
[C:1]([NH2:2])(=[O:3])[CH2:4][CH2:5][CH2:6][CH:7]1[CH2:8][CH2:9][N:10]([C:13]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])[CH2:11][CH2:12]1.[OH:20][C:21]([C:22]([F:23])([F:24])[F:25])=[O:26]>>[C:1]([NH2:2])(=[O:3])[CH2:4][CH2:5][CH2:6][CH:7]1[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 21949352tert-Butyl 4-(3-carbamoylpropyl)piperidine-1-carboxylate

Product 1

HCID 219492354-(Piperidin-4-yl)butanamide

Sources & evidence

ORD record
ord-f8aea78972b14aaab31663448c13cc6c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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