Dichloromethane → 4-(Bromomethyl)-1,1-difluorocyclohexane

HRID 816868Notes

Reaction equation

HRID 816868 reaction equation
[C:30]([Br:31])([Br:32])([Br:33])[Br:34].[Cl:35][CH2:36][Cl:37].[F:1][C:2]1([F:10])[CH2:3][CH2:4][CH:5]([CH2:8][OH:9])[CH2:6][CH2:7]1.[c:11]1([P:12]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:25][cH:26][cH:27][cH:28][cH:29]1>>[F:1][C:2]1([F:10])[CH2:3][CH2:4][CH:5]([CH2:8][Br:31])[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 11205Carbon tetrabromideHCID 11776TriphenylphosphineHCID 21184133(4,4-Difluorocyclohexyl)methanol

Product 1

HCID 533503614-(Bromomethyl)-1,1-difluorocyclohexane

Sources & evidence

ORD record
ord-3eab607901ce41a5bd4985e52e05d103
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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