Tetrahydrofuran → [3-(4-Amino-5-bromo-pyrrolo[2,1-f][1,2,4]triazin-7-yl)-benzyl]-carbamic acid tert-butyl ester
Reaction equation
[Br:26][CH:27]1[C:28](=[O:29])[C:30]([CH3:31])([CH3:32])[CH:33]([Br:34])[C:35]1=[O:36].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][c:9]1[cH:10][c:11](-[c:15]2[cH:16][cH:17][c:18]3[c:19]([NH2:24])[n:20][cH:21][n:22][n:23]23)[cH:12][cH:13][cH:14]1)=[O:25].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][c:9]1[cH:10][c:11](-[c:15]2[cH:16][c:17]([Br:26])[c:18]3[c:19]([NH2:24])[n:20][cH:21][n:22][n:23]23)[cH:12][cH:13][cH:14]1)=[O:25]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-ebb16454b5ae4cd6bb2ba8dcc98127d7
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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